Estriol 0.3% + hyaluronic acid 0.5% face cream.
A prescription facial cream combining estriol 0.3% with hyaluronic acid 0.5% for women noticing dryness, loss of firmness, dullness, texture changes and visible skin ageing around perimenopause and menopause.
Estriol and hydration support, made personal.
Prescription skincare for dryness, firmness, radiance and texture changes, with hyaluronic acid added for hydration support.
Estriol 0.3% + Hyaluronic Acid 0.5%
Root & Radiance Estriol 0.3% + Hyaluronic Acid 0.5% Face Cream is a prescription topical facial cream for women experiencing menopause-related skin changes. It is designed for concerns such as dryness, reduced firmness, dullness, visible fine lines and changes in texture.
Estriol 0.3% is the prescription oestrogen active in the formula. It is used locally on facial skin and may be considered where hormonal changes are affecting skin quality. Hyaluronic acid 0.5% is included to support hydration by helping the skin surface hold onto water, so skin can feel smoother, softer and more comfortable.
Treatment is supplied only if clinically suitable after an online consultation and UK prescriber review. Individual results vary.
Menopause can change the way skin looks and feels.
As oestrogen levels change during perimenopause and menopause, many women notice their skin feels drier, thinner, less firm, less elastic, or slower to recover. This prescription menopause skincare route combines estriol 0.3% with hyaluronic acid 0.5% to pair clinical review with hydration-focused skin support.
Dryness
Changing hormones may affect skin comfort and hydration. Hyaluronic acid helps support a smoother, more hydrated feel.
Firmness
Many women notice reduced firmness and bounce as skin changes around menopause.
Texture
Skin may appear rougher, duller, or less even in texture as hormonal and hydration support change.
Radiance
Estriol skincare may help support a healthier looking glow when used consistently as part of a routine.
Why estriol 0.3% with hyaluronic acid 0.5%?
Estriol is one of the three main forms of oestrogen. In this formula, estriol 0.3% is the prescription active used locally on facial skin for menopause-related skin changes, subject to clinical suitability.
Hyaluronic acid 0.5% is included as a hydration-support ingredient. It helps attract and hold water at the skin surface, supporting a smoother, softer and more comfortable feel while the prescription active is reviewed and used as directed.
Suitability still needs to be reviewed by a clinician, especially if you have a history of hormone-sensitive conditions, unexplained vaginal bleeding, blood clots, liver disease, or if you use other hormone treatments. This product is for facial use only. It is not for vaginal, vulval or internal use.
A simple prescription skincare pathway.
Tell us about your skin
Complete an online questionnaire about your skin, menopause stage, medical history and treatment goals.
Clinical review
A UK registered prescriber reviews your answers to decide whether treatment is suitable.
Pharmacy dispensing
If approved, your prescription is dispensed by our pharmacy partner.
Delivered discreetly
Your treatment is delivered discreetly with guidance on how to use it safely.
Estriol 0.3% with hyaluronic acid 0.5% for menopause-related skin changes
During perimenopause and menopause, many women notice changes in the way their skin looks and feels. These changes can include dryness, reduced firmness, reduced elasticity, a thinner skin feel, dullness, visible texture changes and fine lines.
Estriol 0.3% with hyaluronic acid 0.5% face cream is a prescription skincare option designed for women who want a clinically reviewed route for menopause-related skin concerns. It is not a standard cosmetic moisturiser. It should only be used where a prescriber has confirmed it is appropriate.
What hyaluronic acid 0.5% adds
Hyaluronic acid is a hydration-support ingredient used in skincare because it helps bind water at the skin surface. In this formula it complements the estriol 0.3% route by supporting skin comfort, softness and a more hydrated-looking finish.
Estriol vs estradiol
Estriol and estradiol are both forms of oestrogen, but they are not the same. Estradiol is generally considered more potent and is commonly used in systemic hormone therapy and vaginal hormone treatment. Estriol is considered less potent and is often discussed as a gentler topical option for facial skincare.
Who might consider estriol face cream?
This route may be considered by women in perimenopause, menopause or postmenopause who are noticing skin changes that feel different to their earlier skin pattern. This may include increased dryness, loss of radiance, reduced firmness, fine lines, or a less resilient skin barrier.
How to use estriol cream
Use should follow the instructions provided by your prescriber. In general, prescription face creams are usually applied to clean, dry skin, often in the evening or as directed. Sunscreen should be used during the day, especially if you are also using active skincare ingredients.
Important safety information
Estriol face cream may not be suitable for everyone. You should complete the consultation accurately, especially if you have a history of breast cancer, hormone-sensitive cancer, unexplained vaginal bleeding, blood clots, liver disease, are pregnant, breastfeeding, or are using hormone therapy.
Frequently asked questions
Ready to build your menopause skincare route?
Complete a quick online consultation for estriol 0.3% with hyaluronic acid 0.5%. If suitable, your prescription skincare is reviewed, dispensed and delivered discreetly to your door.