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Prescription menopause skincare, reviewed in the UK

Estriol face cream for changing skin.

A prescription skincare route for women noticing dryness, loss of firmness, dullness, texture changes and visible skin ageing around perimenopause and menopause.

Learn about estriol

Estriol based Designed for menopause-related changes in skin appearance.
Clinical review Reviewed by UK registered prescribers before supply.
UK dispensing Dispensed by our UK pharmacy partner if clinically suitable.
Free delivery Delivered discreetly after approval and dispensing.
Estriol face cream texture and product packaging

Menopause skincare, made personal.

Prescription skincare for dryness, firmness, radiance and texture changes, subject to clinical suitability.

Menopause skincare

Estriol Face Cream

Prescription skincare Estriol 30ml Prescriber reviewed

Root & Radiance Estriol Face Cream is a prescription topical facial cream for women experiencing menopause-related skin changes. It is designed for concerns such as dryness, reduced firmness, dullness, visible fine lines and changes in texture.

Estriol is one of the three main forms of oestrogen. In skincare, topical estriol is used locally on the skin and may be considered where hormonal changes are affecting skin quality.

Treatment is supplied only if clinically suitable after an online consultation and prescriber review.

£50
30ml. Consultation, clinical review and free UK delivery included.
Why skin changes

Menopause can change the way skin looks and feels.

As oestrogen levels change during perimenopause and menopause, many women notice their skin feels drier, thinner, less firm, less elastic, or slower to recover. Prescription menopause skincare is designed to address these changes through a clinically reviewed route.

01

Dryness

Changing hormones may affect skin barrier comfort, leaving skin feeling drier or less supple.

02

Firmness

Many women notice reduced firmness and bounce as skin changes around menopause.

03

Texture

Skin may appear rougher, duller, or less even in texture as collagen and hydration support change.

04

Radiance

Estriol skincare may help support a healthier looking glow when used consistently as part of a routine.

Key ingredient

What is estriol?

Estriol is one of the three main forms of oestrogen. It is generally considered less potent than estradiol and is often discussed as a gentler topical option for facial skincare.

Topical facial estriol is used locally on the skin. Suitability still needs to be reviewed by a clinician, especially if you have a history of hormone-sensitive conditions, unexplained vaginal bleeding, blood clots, liver disease, or if you use other hormone treatments.

This product is for facial use only. It is not for vaginal, vulval or internal use.

Close up of cream texture for prescription skincare
How it works

A simple prescription skincare pathway.

01

Tell us about your skin

Complete an online questionnaire about your skin, menopause stage, medical history and treatment goals.

02

Clinical review

A UK registered prescriber reviews your answers to decide whether treatment is suitable.

03

Pharmacy dispensing

If approved, your prescription is dispensed by our pharmacy partner.

04

Delivered discreetly

Your treatment is delivered discreetly with guidance on how to use it safely.

Menopause skincare UK

Estriol face cream for menopause-related skin changes

During perimenopause and menopause, many women notice changes in the way their skin looks and feels. These changes can include dryness, reduced firmness, reduced elasticity, a thinner skin feel, dullness, visible texture changes and fine lines.

Estriol face cream is a prescription skincare option designed for women who want a clinically reviewed route for menopause-related skin concerns. It is not a standard cosmetic moisturiser. It should only be used where a prescriber has confirmed it is appropriate.

Estriol vs estradiol

Estriol and estradiol are both forms of oestrogen, but they are not the same. Estradiol is generally considered more potent and is commonly used in systemic hormone therapy and vaginal hormone treatment. Estriol is considered less potent and is often discussed as a gentler topical option for facial skincare.

Who might consider estriol face cream?

This route may be considered by women in perimenopause, menopause or postmenopause who are noticing skin changes that feel different to their earlier skin pattern. This may include increased dryness, loss of radiance, reduced firmness, fine lines, or a less resilient skin barrier.

How to use estriol cream

Use should follow the instructions provided by your prescriber. In general, prescription face creams are usually applied to clean, dry skin, often in the evening or as directed. Sunscreen should be used during the day, especially if you are also using active skincare ingredients.

Important safety information

Estriol face cream may not be suitable for everyone. You should complete the consultation accurately, especially if you have a history of breast cancer, hormone-sensitive cancer, unexplained vaginal bleeding, blood clots, liver disease, are pregnant, breastfeeding, or are using hormone therapy.

Common questions

Frequently asked questions

Yes. Root & Radiance Estriol Face Cream is treated as a prescription skincare product. You complete an online consultation first, then a prescriber reviews whether it is suitable before it can be dispensed.
No. Estriol and estradiol are both forms of oestrogen, but estradiol is generally considered more potent. Estriol is often discussed as a gentler topical option for facial skincare, but it still needs clinical review before use.
Possibly, but the prescriber needs to know exactly what HRT or hormonal treatments you use. The consultation asks about oestrogen, progesterone, testosterone, Mirena coil and other hormone treatments so suitability can be assessed.
Skin changes usually take time. Many prescription skincare routines need consistent use for several weeks before changes in dryness, texture, firmness or radiance become noticeable. Your prescriber will advise how to use it safely.
You should tell us if you use tretinoin, retinoids, exfoliating acids or strong active skincare. Combining actives may increase irritation, so the prescriber may advise spacing products, adjusting frequency, or using a simpler routine.
It may not be suitable if you are pregnant, trying to conceive or breastfeeding, or if you have a history of breast cancer, womb cancer, ovarian cancer, unexplained vaginal bleeding, blood clots, stroke, heart disease or liver disease. The prescriber will review your answers before deciding.

Ready to build your menopause skincare route?

Complete a quick online consultation. If suitable, your prescription skincare is reviewed, dispensed and delivered discreetly to your door.

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